1.0.0.0 Recommendations and GRADE
1.1.0.0 Recommendations
Sr.no. |
Recommendations |
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1 |
In patients with chronic hepatitis C, the AGA recommends VCTE, if available, rather than other nonproprietary, noninvasive serum tests (APRI, FIB-4) to detect cirrhosis. |
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2 |
In patients with chronic hepatitis C, the AGA suggests a VCTE cutoff of 12.5 kPa to detect cirrhosis. |
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3 |
In noncirrhotic patients with HCV who have achieved SVR after antiviral therapy, the AGA suggests a post-treatment vibration controlled transient elastography cutoff of 9.5 kPa to rule out advanced liver fibrosis. |
Cond |
V Low |
4 |
In patients with chronic hepatitis B, the AGA suggests VCTE rather than other nonproprietary noninvasive serum tests (ie, APRI and FIB-4) to detect cirrhosis. |
Cond |
Low |
5 |
In patients with chronic hepatitis B, the AGA suggests a VCTE cutoff of 11.0 kPa to detect cirrhosis. |
Cond |
Low |
6 |
The AGA makes no recommendation regarding the role of VCTE in the diagnosis of cirrhosis in adults with NAFLD. |
N/A |
N/A |
7 |
In patients with chronic alcoholic liver disease, the AGA suggests a VCTE cutoff of 12.5 kPa to detect cirrhosis. |
Cond |
Low |
8 |
In patients with suspected compensated cirrhosis, the AGA suggests a vibration controlled transient elastography cutoff of 19.5 kPa to assess the need for esophagogastroduodenoscopy to identify high risk esophageal varices. |
Cond |
Low |
9 |
In patients with suspected chronic liver disease undergoing elective nonhepatic surgery, the AGA suggests a VCTE cutoff of 17.0 kPa to detect clinically significant portal hypertension to inform preoperative care. |
Cond |
Low |
10 |
In adult patients with chronic hepatitis C, the AGA suggests using VCTE rather than MRE for detection of cirrhosis. |
Cond |
V Low |
11 |
In adults with NAFLD and a higher risk of cirrhosis, the AGA suggest using MRE, rather than VCTE, for detection of cirrhosis. |
Cond |
Low |
In adults with NAFLD and a lower risk of cirrhosis, the AGA makes no recommendation regarding the role of MRE or VCTE for detection of cirrhosis. |
N/A |
N/A |
|
SoR: Strength of Recommendation
QoE: Quality of Evidence
Strong: Strong Recommendation
Cond: Conditional Recommendation
High: High-Quality Evidence
Mod: Moderate-Quality Evidence
Low: Low-Quality Evidence
V Low: Very Low-Quality Evidence