Tämä on keskustelufoorumin arkisto, jonne on koottu keskustelut Syöpäjärjestöjen vanhoilta verkkosivuilta. Keskustelujen viestejä voi lukea, mutta viestejä ei pysty kirjoittamaan.Siirry uudelle keskustelufoorumille.

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Re: Eturauhassyöpä Käypä hoito 14.11.2007

Hei
Nuo kirjaimet tarkoittavat alkuperäistutkimusten perusteella arvioitua näytön astetta: A = vahva tutkimusnäyttö, B = kohtalainen tutkimusnäyttö, C = vähäinen tutkimusnäyttö, D = asiantuntijamielipide (heikko tutkimusnäyttö).
Tuossa beetakaroteeni/porkkana-asiassa on kyllä sellaisiakin tutkimuksia julkaistu, joissa ei yhteyttä ole voitu osoittaa. Tieteellisen tiedon tulkinta onkin hankalaa, kun ristiriitaista tutkimustulosta pukkaa. Eiköhän uskalleta syödä porkkanaa kohtuullisessa määrin kuitenkin?

Fam Pract. 2011 Jun;28(3):243-52. doi: 10.1093/fampra/cmq115. Epub 2011 Jan 27.
The effect of supplemental vitamins and minerals on the development of prostate cancer: a systematic review and meta-analysis.
Stratton J, Godwin M.
Source
Primary Healthcare Research Unit, Agnes Cowan Hostel, St. John's Newfoundland, A1B 3V6, Canada.
Abstract
BACKGROUND:
Vitamin supplementation is used for many purposes with mainly alleged benefits. One of these is the use of various vitamins for the prevention of prostate cancer.
METHODS:
We conducted a systematic review and meta-analysis on this topic. Pubmed, Embase and the Cochrane Database were searched; as well, we hand searched the references in key articles. Randomized controlled trials (RCTs), cohort studies and case-control studies were included. The review assessed the effect of supplemental vitamins on the risk of prostate cancer and on disease severity and death in men with prostate cancer.
RESULTS:
Fourteen articles were included in the final assessment. Individually, a few of these studies showed a relationship between the ingestion of supplemental vitamins or minerals and the incidence or severity of prostate cancer, especially in smokers. However, neither the use of multivitamin supplementation nor the use of individual vitamin/mineral supplementation affected the overall occurrence of prostate cancer or the occurrence of advanced/metastatic prostate cancer or death from prostate cancer when the results of the studies were combined in a meta-analysis. We also conducted several sensitivity analyses by running meta-analysis using just the higher quality studies and just the RCTs. There were still no associations found.
CONCLUSIONS:
There is no convincing evidence that the use of supplemental multivitamins or any specific vitamin affects the occurrence or severity of prostate cancer. There was high heterogeneity among the studies so it is possible that unidentified subgroups may benefit or be harmed by the use of vitamins.
Watson | 18.2.2013 klo 19:06:44